A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

2상 완료 NCT04090411

요약

This phase 2b study is designed to have all subjects go into a 12 week induction period to compare different doses of study drug against placebo. After induction is complete all subjects will receive active therapy for 40 weeks, followed by a 12 week follow up period.

Induction Period: Percentage of Participants Who Achieved Clinical Remission at Week 14

At Week 14 · percentage of participants

Induction Period: Number of Participants With Treatment-Emergent Adverse Events (TEAEs)

From initiation of study treatment to either first dose in the chronic period or end of safety follow-up, whichever occurs first. (Approximately 16 weeks plus 12-week safety follow-up, if applicable.) · Participants

Induction Period: Number of Participants With Serious Adverse Events (SAEs)

From initiation of study treatment to either first dose in the chronic period or end of safety follow-up, whichever occurs first. (Approximately 16 weeks plus 12-week safety follow-up, if applicable.) · Participants

BENITIONS에서 보기 ClinicalTrials.gov 원문 보기

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