Androgen Deprivation Therapy Prior to Prostatectomy for Patients With Intermediate and High Risk Prostate Cancer
| 대상 질환 | Prostate Cancer, Prostatic Adenocarcinoma |
|---|---|
| 임상 단계 | 단계 해당 없음 |
| 스폰서 | Memorial Sloan Kettering Cancer Center |
| 상태 | 완료 |
| 참여자 수 | 41 명 |
| 중재(약물) | degarelix injection, degarelix injection, androgen deprivation therapy |
| 시작일 | 2012년 2월 24일 |
| 완료일 | 2024년 9월 30일 |
| 결과 공개일 | 2026년 7월 29일 |
요약
Degarelix is an approved drug that is used to treat prostate cancer by lowering testosterone levels in the body. Degarelix is commonly given with radiation for prostate cancer, but less frequently with surgery since there has been no proven benefit with this approach. The investigators do not expect the patient to benefit directly from treatment with degarelix since their prostate will be removed shortly after the drug is given. Instead, the investigators hope to learn about how degarelix and other treatment that lowers your testosterone effects prostate cancer cells and use this information to develop better treatments in the future.
Percent Change in Prostate Cancer Cell Proliferation (Ki-67 Levels)
| Untreated Patients Degarelix Injection Occur at Days 4± 1 | 32 percent change |
|---|---|
| Untreated Patients Degarelix Injection Occur at Days and 7± 1. | 27 percent change |
| Untreated Patients With Androgen Deprivation | 88 percent change |
| Untreated Patients Degarelix Injection Occur at Days 14±1 | NA percent change |
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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