BENITIONSClinical Trial Intelligence

Sleep and Circadian Mechanisms of Non-dipping Blood Pressure

該当なし 完了 NCT03558893

対象疾患Hypertension, Cardiovascular Risk Factor
該当なし
スポンサーOregon Health and Science University
ステータス完了
参加者数30 名
介入(薬剤)Forced Desynchrony
開始日2018年12月1日
完了日2024年12月31日
結果公開日2026年6月16日

概要

This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on mechanisms, such as targeting sleep, targeting circadian rhythmicity, or targeting behaviors, and raising the possibility that ideal therapy for hypertension (HTN) may differ by race. This research will ultimately help to improve health and survival in black populations with HTN.

Nighttime Systolic Blood Pressure

Baseline Night Average · mmHg

White Adults101.6 ± 2.1 mmHg
Black Adults92.4 ± 4.0 mmHg

Nighttime Diastolic Blood Pressure

Baseline Night Average · mmHg

White Adults60.5 ± 1.4 mmHg
Black Adults59.0 ± 1.4 mmHg

Daytime Systolic Blood Pressure

Baseline Daytime Average · mmHg

White Adults116.6 ± 8.6 mmHg
Black Adults120.5 ± 9.7 mmHg

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