A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes
3期
已完成
NCT06340854
| 适应症 | Diabetes, Type 2 |
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| 分期 | 3期 |
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| 申办方 | Novo Nordisk A/S |
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| 状态 | 已完成 |
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| 受试者人数 | 412 人 |
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| 干预(药物) | Insulin icodec, Insulin glargine |
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| 开始日期 | 2024年4月19日 |
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| 完成日期 | 2025年5月8日 |
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| 结果公布日 | 2026年7月2日 |
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摘要
This study compares insulin icodec, a new insulin taken once a week, to insulin glargine, an insulin taken once a day. The study medicine will be investigated in participants with type 2 diabetes. Participants will either get insulin icodec or insulin glargine. Which treatment participants get is decided by chance. Insulin icodec is the new medicine being tested, while insulin glargine is already approved and can be prescribed by doctors. Participants will get one injection of insulin icodec once a week, or one injection of insulin glargine once a day, depending on the treatment group participants are assigned into. Participants will use a pen with a small needle to inject the medicine under participants skin into participants thigh, upper arm or stomach.The study will last for about 9 months, but participants will only be taking the study medicine for 6 months.
Change in Glycated Haemoglobin (HbA1c)
Week 0, Week 26 · Percentage (%) point
| Insulin Icodec | -0.84 ± 0.83 Percentage (%) point |
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| Insulin Glargine | -0.58 ± 0.89 Percentage (%) point |
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| p-value | <0.0001 |
| Treatment difference | -0.21 (95% CI -0.36–-0.07) |
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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。