BENITIONSClinical Trial Intelligence

A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes

3상 완료 NCT06340854

대상 질환Diabetes, Type 2
임상 단계3상
스폰서Novo Nordisk A/S
상태완료
참여자 수412 명
중재(약물)Insulin icodec, Insulin glargine
시작일2024년 4월 19일
완료일2025년 5월 8일
결과 공개일2026년 7월 2일

요약

This study compares insulin icodec, a new insulin taken once a week, to insulin glargine, an insulin taken once a day. The study medicine will be investigated in participants with type 2 diabetes. Participants will either get insulin icodec or insulin glargine. Which treatment participants get is decided by chance. Insulin icodec is the new medicine being tested, while insulin glargine is already approved and can be prescribed by doctors. Participants will get one injection of insulin icodec once a week, or one injection of insulin glargine once a day, depending on the treatment group participants are assigned into. Participants will use a pen with a small needle to inject the medicine under participants skin into participants thigh, upper arm or stomach.The study will last for about 9 months, but participants will only be taking the study medicine for 6 months.

Change in Glycated Haemoglobin (HbA1c)

Week 0, Week 26 · Percentage (%) point

Insulin Icodec-0.84 ± 0.83 Percentage (%) point
Insulin Glargine-0.58 ± 0.89 Percentage (%) point
p-value<0.0001
Treatment difference-0.21 (95% CI -0.36–-0.07)

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