Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer
| 适应症 | Invasive Breast Cancer |
|---|---|
| 分期 | 2期 |
| 申办方 | Medical College of Wisconsin |
| 状态 | 进行中（已停止招募） |
| 受试者人数 | 36 人 |
| 干预（药物） | Cemiplimab, Paclitaxel, Carboplatin (not mandatory), Doxorubicin, Cyclophosphamide |
| 开始日期 | 2020年3月5日 |
| 完成日期 | 2025年8月11日 |
| 结果公布日 | 2026年7月27日 |
摘要
This is a single-arm, open-label, phase 2 study that will enroll 36 subjects, who have pathologically proven diagnosis of invasive breast cancer, clinical stage tumor 1-3 (cT1-T3), node 0-3 (cN0-N3), metastasis 0 (cM0), hormone receptor positive (HR+) (estrogen-receptor-positive (ER+) and/or progesterone-receptor-positive (PR+) human epidermal growth factor receptor 2 (HER2) negative or hormone receptor-negative (HR-) (estrogen-receptor-negative (ER-) and progesterone-receptor-negative (PR-) human epidermal growth factor receptor 2 (HER2) negative/triple-negative breast cancer.
The Proportion of Breast Cancer Patients With Pathological Complete Response (pCR).
| Drug Treatment | 24.2 percentage of subjects |
|---|---|
| Drug Treatment | 75.8 percentage of subjects |
在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文
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