Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer
| Condition | Invasive Breast Cancer |
|---|---|
| Phase | Phase 2 |
| Sponsor | Medical College of Wisconsin |
| Status | Active, not recruiting |
| Enrollment | 36 participants |
| Interventions | Cemiplimab, Paclitaxel, Carboplatin (not mandatory), Doxorubicin, Cyclophosphamide |
| Start date | Mar 5, 2020 |
| Completion date | Aug 11, 2025 |
| Results posted | Jul 27, 2026 |
Summary
This is a single-arm, open-label, phase 2 study that will enroll 36 subjects, who have pathologically proven diagnosis of invasive breast cancer, clinical stage tumor 1-3 (cT1-T3), node 0-3 (cN0-N3), metastasis 0 (cM0), hormone receptor positive (HR+) (estrogen-receptor-positive (ER+) and/or progesterone-receptor-positive (PR+) human epidermal growth factor receptor 2 (HER2) negative or hormone receptor-negative (HR-) (estrogen-receptor-negative (ER-) and progesterone-receptor-negative (PR-) human epidermal growth factor receptor 2 (HER2) negative/triple-negative breast cancer.
The Proportion of Breast Cancer Patients With Pathological Complete Response (pCR).
| Drug Treatment | 24.2 percentage of subjects |
|---|---|
| Drug Treatment | 75.8 percentage of subjects |
Open in BENITIONS View on ClinicalTrials.gov
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