BENITIONSClinical Trial Intelligence

Durvalumab and Tremelimumab in Treating Participants With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

2期 已完成 NCT03026062

适应症Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Ovarian Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Recurrent Fallopian Tube Carcinoma
分期2期
申办方M.D. Anderson Cancer Center
状态已完成
受试者人数100 人
干预(药物)Durvalumab, Tremelimumab
开始日期2017年5月18日
完成日期2025年9月11日
结果公布日2026年8月5日

摘要

This phase II trial studies how well durvalumab and tremelimumab work in treating participants with ovarian, primary peritoneal, or fallopian tube cancer that has come back or does not respond to treatment. Immunotherapy with monoclonal antibodies, such as durvalumab and tremelimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. It is not yet known whether give durvalumab and tremelimumab in combination or sequential administration works better in treating participants with ovarian, primary peritoneal, or fallopian tube cancer.

Immune-related Progression-free Survival (irPFS)

63 months · months

Sequential Arm - High Grade Serous1.84 months
Combination Arm - High Grade Serous1.87 months
Sequential Arm - Clear Cell1.4 months
Combination Arm - Clear Cell2.32 months

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。