The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis
Phase 2
Completed
NCT05772520
| Condition | Plaque Psoriasis |
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| Phase | Phase 2 |
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| Sponsor | Hangzhou Highlightll Pharmaceutical Co., Ltd |
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| Status | Completed |
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| Enrollment | 82 participants |
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| Interventions | TLL018 tablets |
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| Start date | Jan 19, 2023 |
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| Completion date | Dec 1, 2024 |
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| Results posted | Jul 21, 2026 |
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Summary
This is a Phase 2, multicenter, randomized, double-blinded, parallel dose group, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of 2 doses of TLL018 as therapy in approximately 90 participants with moderate-to-severe PP.
Proportion of Participants Achieving PASI-75 (FAS)
Week12 · Participants
| Cohort 1 | 11 Participants |
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| Cohort 2 | 13 Participants |
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| Cohort 3 | 4 Participants |
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| Cohort 4 | 3 Participants |
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Proportion of Participants Achieving PASI 75 (PPS)
Week12 · Participants
| Cohort 1 | 9 Participants |
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| Cohort 2 | 11 Participants |
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| Cohort 3 | 4 Participants |
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| Cohort 4 | 2 Participants |
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Open in BENITIONS
View on ClinicalTrials.gov
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