BENITIONSClinical Trial Intelligence

Fast Arm Motor Skill Training in Chronic Stroke Survivors

N/A Completed NCT05013762

ConditionCerebrovascular Stroke
PhaseN/A
SponsorUniversity of Southern California
StatusCompleted
Enrollment44 participants
InterventionsFast intervention, Active Monitoring
Start dateJun 15, 2021
Completion dateSep 1, 2023
Results postedJun 26, 2026

Summary

Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation. 1) The primary objective of this study is to determine whether fast arm movement training on a tracking task ("Speed-training"), in chronic stroke survivors with mild to moderate paresis, will generalize to improve arm function better than dose-equivalent accuracy training on the same task. 2) study the effect of intensive arm training on the recovery of anticipatory feedforward control. 3) Determine the involvement of cerebellar-cortical circuits in the recovery of arm movements due to speed training.

Change in Arm Reaching Movement Time.

Change from baseline (assessed during the week preceding the intervention) to 3 days post-intervention, representing an average interval of 12 days · seconds

Speed-biased Complex Motor Skill Training-0.13 ± 0.001 seconds
Accuracy-biased Complex Motor Skill Training0.07 ± 0.0004 seconds

Change in Movement Smoothness

Change from baseline (assessed during the week preceding the intervention) to 3 days post-intervention, representing an average interval of 12 days · number of peaks

Speed-biased Complex Motor Skill Training-0.43 ± 0.008 number of peaks
Accuracy-biased Complex Motor Skill Training-0.1 ± 0.005 number of peaks

Change in Speed Accuracy Trade-off

Change from baseline (assessed during the week preceding the intervention) to 3 days post-intervention, representing an average interval of 12 days · Fitts' slope (sec/index of difficulty)

Speed-biased Complex Motor Skill Training-0.034 ± 0.014 Fitts' slope (sec/index of difficulty)
Accuracy-biased Complex Motor Skill Training0.033 ± 0.018 Fitts' slope (sec/index of difficulty)

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