BENITIONSClinical Trial Intelligence

Fast Arm Motor Skill Training in Chronic Stroke Survivors

단계 해당 없음 완료 NCT05013762

대상 질환Cerebrovascular Stroke
임상 단계단계 해당 없음
스폰서University of Southern California
상태완료
참여자 수44 명
중재(약물)Fast intervention, Active Monitoring
시작일2021년 6월 15일
완료일2023년 9월 1일
결과 공개일2026년 6월 26일

요약

Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation. 1) The primary objective of this study is to determine whether fast arm movement training on a tracking task ("Speed-training"), in chronic stroke survivors with mild to moderate paresis, will generalize to improve arm function better than dose-equivalent accuracy training on the same task. 2) study the effect of intensive arm training on the recovery of anticipatory feedforward control. 3) Determine the involvement of cerebellar-cortical circuits in the recovery of arm movements due to speed training.

Change in Arm Reaching Movement Time.

Change from baseline (assessed during the week preceding the intervention) to 3 days post-intervention, representing an average interval of 12 days · seconds

Speed-biased Complex Motor Skill Training-0.13 ± 0.001 seconds
Accuracy-biased Complex Motor Skill Training0.07 ± 0.0004 seconds

Change in Movement Smoothness

Change from baseline (assessed during the week preceding the intervention) to 3 days post-intervention, representing an average interval of 12 days · number of peaks

Speed-biased Complex Motor Skill Training-0.43 ± 0.008 number of peaks
Accuracy-biased Complex Motor Skill Training-0.1 ± 0.005 number of peaks

Change in Speed Accuracy Trade-off

Change from baseline (assessed during the week preceding the intervention) to 3 days post-intervention, representing an average interval of 12 days · Fitts' slope (sec/index of difficulty)

Speed-biased Complex Motor Skill Training-0.034 ± 0.014 Fitts' slope (sec/index of difficulty)
Accuracy-biased Complex Motor Skill Training0.033 ± 0.018 Fitts' slope (sec/index of difficulty)

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