Deep Brain Stimulation for Treatment Resistant Depression
| Condition | Major Depressive Disorder |
|---|---|
| Phase | N/A |
| Sponsor | Emory University |
| Status | Completed |
| Enrollment | 37 participants |
| Interventions | Deep Brain Stimulation |
| Start date | Sep, 2006 |
| Completion date | Jan 2, 2014 |
| Results posted | Jul 14, 2020 |
Summary
The purpose of this study is to test the safety, efficacy and mechanism of action of subgenual cingulate (Cg25) deep brain stimulation (DBS) for major depression in patients who have not responded to prior antidepressant treatments. Participation in the study will continue for ten years or until the device receives FDA approval for depression. Forty (40) patients will be enrolled in this study.
Change in Hamilton Depression Rating Scale-17 Score
| Deep Brain Stimulation | 23.6 ± 2.9 score on a scale |
|---|---|
| Deep Brain Stimulation | 11.66 ± 2.6 score on a scale |
Open in BENITIONS View on ClinicalTrials.gov
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- Severe Asthma, MepolizumaB and Affect: SAMBA Study — University Hospital Southampton NHS Foundation Trust
- Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for — Levomecor Inc.
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- Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders — Massachusetts General Hospital