BENITIONSClinical Trial Intelligence

Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)

Phase 3 Completed NCT00337571

ConditionBehavioral Symptoms, Autistic Disorder
PhasePhase 3
SponsorOtsuka Pharmaceutical Development & Commercialization, Inc.
StatusCompleted
Enrollment218 participants
InterventionsAripiprazole
Start dateJun 1, 2006
Completion dateJun 1, 2008
Results postedJul 23, 2009

Summary

This study will compare the effectiveness (how well the drug works) of aripiprazole with placebo (fixed dose) in reducing serious behavioral problems in children and adolescents with a diagnosis of autistic disorder (AD).

Mean Change (Week 8 - Baseline) in the Autistic Behavior Checklist (ABC) Irritability Subscale Score

Week 8 · units on a scale

Placebo-8.4 ± 1.39 units on a scale
Aripiprazole 5 mg-12.4 ± 1.36 units on a scale
Aripiprazole 10 mg-13.2 ± 1.25 units on a scale
Aripiprazole 15 mg-14.4 ± 1.31 units on a scale

Open in BENITIONS View on ClinicalTrials.gov

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