A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)
3期
已完成
NCT05899816
| 适应症 | Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis |
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| 分期 | 3期 |
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| 申办方 | Amgen |
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| 状态 | 已完成 |
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| 受试者人数 | 221 人 |
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| 干预(药物) | Rocatinlimab |
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| 开始日期 | 2023年6月7日 |
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| 完成日期 | 2024年8月26日 |
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| 结果公布日 | 2026年7月23日 |
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摘要
The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 24
Percentage of Participants With a Positive Anti-tetanus Response at Week 24
Week 20 to Week 24 · percentage of participants
| Placebo | 92.3 percentage of participants |
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| Rocatinlimab | 87.6 percentage of participants |
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| Risk Difference (RD) | -4.7 (95% CI -13.5–5.9) |
Percentage of Participants With a Positive Anti-meningococcal Response at Week 24
Week 20 to Week 24 · percentage of participants
| Placebo | 53.2 percentage of participants |
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| Rocatinlimab | 52.5 percentage of participants |
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| Risk Difference (RD) | -0.7 (95% CI -18.3–17.1) |
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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。