Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent
| Заболевание | Arthritis, Psoriatic |
|---|---|
| Фаза | Фаза 3 |
| Спонсор | Janssen Research & Development, LLC |
| Статус | Идёт, набор закрыт |
| Участники | 453 участн. |
| Вмешательство | Guselkumab |
| Дата начала | 28.09.2021 |
| Дата завершения | 28.10.2024 |
| Публикация результатов | 8.12.2025 |
Кратко
The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 24
| Placebo Followed by Guselkumab 100 mg | 35.9 Percentage of participants |
|---|---|
| Guselkumab 100 mg q8w | 63.0 Percentage of participants |
| Guselkumab 100 mg q4w | 60.9 Percentage of participants |
Открыть в BENITIONS Открыть на ClinicalTrials.gov
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