Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)
| 대상 질환 | Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Refractory Lymphoma, Refractory Malignant Solid Neoplasm |
|---|---|
| 임상 단계 | 2상 |
| 스폰서 | National Cancer Institute (NCI) |
| 상태 | 진행 중(모집 완료) |
| 참여자 수 | 10 명 |
| 중재(약물) | Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging |
| 시작일 | 2016년 11월 1일 |
| 완료일 | 2023년 4월 5일 |
| 결과 공개일 | 2025년 3월 19일 |
요약
This phase II MATCH treatment trial tests how well sunitinib in treating patients with cancer that has certain genetic changes. Sunitinib is in a class of medications called kinase inhibitors. It is used in patients whose cancer has a certain mutation (change) in the cKIT gene. It works by blocking the action of mutated cKIT that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Objective Response Rate (ORR)
| Treatment (Sunitinib) | 22.2 percentage of participants |
|---|
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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