BENITIONSClinical Trial Intelligence

Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)

2상 진행 중(모집 완료) NCT06390826

대상 질환Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Refractory Lymphoma, Refractory Malignant Solid Neoplasm
임상 단계2상
스폰서National Cancer Institute (NCI)
상태진행 중(모집 완료)
참여자 수10 명
중재(약물)Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging
시작일2016년 11월 1일
완료일2023년 4월 5일
결과 공개일2025년 3월 19일

요약

This phase II MATCH treatment trial tests how well sunitinib in treating patients with cancer that has certain genetic changes. Sunitinib is in a class of medications called kinase inhibitors. It is used in patients whose cancer has a certain mutation (change) in the cKIT gene. It works by blocking the action of mutated cKIT that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Objective Response Rate (ORR)

Tumor assessments occurred at baseline, then every 3 months if patient is < 2 years from study entry, and every 6 months thereafter until disease progression, up to 3 years post registration · percentage of participants

Treatment (Sunitinib)22.2 percentage of participants

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