Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)
| 适应症 | Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Refractory Lymphoma, Refractory Malignant Solid Neoplasm |
|---|---|
| 分期 | 2期 |
| 申办方 | National Cancer Institute (NCI) |
| 状态 | 进行中(已停止招募) |
| 受试者人数 | 10 人 |
| 干预(药物) | Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging |
| 开始日期 | 2016年11月1日 |
| 完成日期 | 2023年4月5日 |
| 结果公布日 | 2025年3月19日 |
摘要
This phase II MATCH treatment trial tests how well sunitinib in treating patients with cancer that has certain genetic changes. Sunitinib is in a class of medications called kinase inhibitors. It is used in patients whose cancer has a certain mutation (change) in the cKIT gene. It works by blocking the action of mutated cKIT that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Objective Response Rate (ORR)
| Treatment (Sunitinib) | 22.2 percentage of participants |
|---|
在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文
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