A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

3상 완료 NCT06034743

요약

This is a Phase III, multicentre, randomised, double-blinded, placebo-controlled, parallel group study to evaluate the safety, tolerability and effect of 1 or 2 mg baxdrostat versus placebo, administered once daily (QD) orally, on the reduction of systolic blood pressure in approximately 720 participants aged ≥ 18 years with hypertension, despite a stable regimen of 2 antihypertensive agents at baseline, one of which is a diuretic (uncontrolled hypertension); or ≥ 3 antihypertensive agents at baseline, one of which is a diuretic (treatment-resistant hypertension).

Change From Baseline in Seated Systolic Blood Pressure for 2 mg Baxdrostat

At Week 12 · mmHg

Change From Baseline in Seated Systolic Blood Pressure for 1 mg Baxdrostat

At Week 12 · mmHg

BENITIONS에서 보기 ClinicalTrials.gov 원문 보기

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