BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort
| 대상 질환 | Atopic Dermatitis, Skin Diseases, Eczema |
|---|---|
| 임상 단계 | 단계 해당 없음 |
| 스폰서 | Women's College Hospital |
| 상태 | 조기 종료 |
| 참여자 수 | 69 명 |
| 중재(약물) | Narrowband UVB phototherapy, Broadband UVB phototherapy |
| 시작일 | 2021년 9월 27일 |
| 완료일 | 2025년 6월 5일 |
| 결과 공개일 | 2026년 7월 21일 |
요약
Atopic dermatitis (eczema) is a complicated skin condition. In fact, it represents many different underlying problems. These include abnormalities in the skin barrier, the immune system and the ability to handle different bacteria. Despite many recent gains in the understanding of eczema, a lot needs to be learned. There is little evidence to select between some of the older treatments that are available now. Even the newest targeted therapy does not clear most patients' skin. In order to improve the understanding of eczema, how to treat it now, and to enable discovery of new treatments, the investigators plan to enroll patients into a large study at three centres in Canada (University of Toronto, McGill University and University of British Columbia). The study is called the Canadian Atopic Dermatitis Cohort for Translational Immunology and Imaging (CACTI). In this study, the investigators will collect data on how severe participants' eczema is and what treatments they use. For participants who give permission, the investigators will collect blood and skin biopsy samples to study the mechanisms underlying their disease. The investigators will test to see which form of phototherapy
Absolute Change From Baseline (95% CrI) in the Eczema Area and Severity Index (EASI)
| Narrowband UVB | -8.9 units on a scale |
|---|---|
| Broadband UVB | -8.1 units on a scale |
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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