BENITIONSClinical Trial Intelligence

BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort

該当なし 早期終了 NCT04818138

対象疾患Atopic Dermatitis, Skin Diseases, Eczema
該当なし
スポンサーWomen's College Hospital
ステータス早期終了
参加者数69 名
介入(薬剤)Narrowband UVB phototherapy, Broadband UVB phototherapy
開始日2021年9月27日
完了日2025年6月5日
結果公開日2026年7月21日

概要

Atopic dermatitis (eczema) is a complicated skin condition. In fact, it represents many different underlying problems. These include abnormalities in the skin barrier, the immune system and the ability to handle different bacteria. Despite many recent gains in the understanding of eczema, a lot needs to be learned. There is little evidence to select between some of the older treatments that are available now. Even the newest targeted therapy does not clear most patients' skin. In order to improve the understanding of eczema, how to treat it now, and to enable discovery of new treatments, the investigators plan to enroll patients into a large study at three centres in Canada (University of Toronto, McGill University and University of British Columbia). The study is called the Canadian Atopic Dermatitis Cohort for Translational Immunology and Imaging (CACTI). In this study, the investigators will collect data on how severe participants' eczema is and what treatments they use. For participants who give permission, the investigators will collect blood and skin biopsy samples to study the mechanisms underlying their disease. The investigators will test to see which form of phototherapy

Absolute Change From Baseline (95% CrI) in the Eczema Area and Severity Index (EASI)

Week 12 · units on a scale

Narrowband UVB-8.9 units on a scale
Broadband UVB-8.1 units on a scale

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