Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

2상 진행 중(모집 완료) NCT02314169

요약

This phase II trial studies how well nivolumab with or without ipilimumab works in treating patients with anal canal cancer that has not responded to previous treatment (refractory) and that has spread from where it first started (primary site) to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Overall Response Rate: Number of Participants With Response (Part A)

Up to 2 years · percentage of patients with a response

Progression-free Survival (PFS) (Part B)

Time period from the date of randomization to the date of PD or death whichever occurred first, assessed up to 2 years · months

BENITIONS에서 보기 ClinicalTrials.gov 원문 보기

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