Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

不适用 已完成 NCT04380311

摘要

Immunosuppressive therapy is required to prevent organ rejection, however, dosing of immunosuppressive agents is complicated by patient-specific differences impacting the body's absorption and elimination of these agents. The goal of this research proposal is to clinically validate an innovative precision medicine strategy for dosing the immunosuppressant tacrolimus in pediatric heart transplant, which will in turn lead to improvements in long-term transplant survival outcomes. The strategy and techniques used in this project can be extended to improve drug therapy across multiple pediatric diseases requiring chronic therapy.

Time to Target Concentration Attainment

Within 6 weeks following transplant · days

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

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