Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis

1期 已完成 NCT03241784

摘要

Open-label pilot study to determine the safety and tolerability of autologous CD4+ CD25+ regulatory T cells infusions with concomitant subcutaneous IL-2 injections taken 3 times per week in 3 participants with ALS.

Number of Participants With Treatment-related Adverse Events as Assessed by Common Terminology Criteria for Adverse Events (CTCAE v4.0) & Medical Dictionary for Regulatory Activities (MedDRA).

Adverse events related to Treg infusions at Baseline to up to two years or study participation, whichever is occurs first. · Participants

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