Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents
| Condition | Asthma |
|---|---|
| Phase | N/A |
| Sponsor | University of North Carolina, Chapel Hill |
| Status | Completed |
| Enrollment | 40 participants |
| Start date | Jul 27, 2021 |
| Completion date | Feb 8, 2024 |
| Results posted | Jun 29, 2026 |
Summary
To study the change from baseline in IL-1β (interleukin 1 beta) concentrations in the nasal airway during acute asthma exacerbation, specifically to measure the degree of change and identify the timing of peak IL-1β concentration. This information will allow the investigators to estimate effect size and guide decisions about the optimal timing of anakinra administration for the future study.
Percentage Change From Baseline in Nasal IL-1β (pg/mL) Concentrations During Asthma Exacerbation
| All Participants | 171.4 percentage change from baseline |
|---|
Open in BENITIONS View on ClinicalTrials.gov
Other trials for this condition
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- Developing a Childhood Asthma Risk Passive Digital Marker — Indiana University
- A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With C — Chiesi Farmaceutici S.p.A.
- A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to — Hoffmann-La Roche
- A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Cortic — Hoffmann-La Roche
- Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Sev — AstraZeneca