Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)
Phase 4
Completed
NCT04363697
| Condition | Acute Heart Failure, Heart Failure |
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| Phase | Phase 4 |
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| Sponsor | The TIMI Study Group |
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| Status | Completed |
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| Enrollment | 2,401 participants |
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| Interventions | Dapagliflozin |
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| Start date | Sep 24, 2020 |
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| Completion date | Jun 2, 2025 |
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| Results posted | Jun 16, 2026 |
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Summary
This is an international, multicenter, parallel-group, randomized, double-blind, placebo-controlled trial in patients who have been stabilized during hospitalization for acute heart failure, evaluating the effect of in-hospital initiation of dapagliflozin versus placebo on the clinical outcome of cardiovascular death or worsening heart failure.
Participants With the Composite Outcome of Cardiovascular Death or Worsening Heart Failure
2 months · Participants
| Dapagliflozin | 133 Participants |
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| Placebo | 150 Participants |
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| p-value | 0.20 |
| Hazard Ratio (HR) | 0.86 (95% CI 0.68–1.08) |
Open in BENITIONS
View on ClinicalTrials.gov
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