Mechanism and Effects of Manipulating Chloride Homeostasis in Acute Heart Failure
| Condition | Heart Failure |
|---|---|
| Phase | Early Phase 1 |
| Sponsor | Yale University |
| Status | Completed |
| Enrollment | 50 participants |
| Interventions | Lysine Chloride |
| Start date | Jul 12, 2018 |
| Completion date | Sep 7, 2022 |
| Results posted | Jan 30, 2024 |
Summary
The purpose of this study is to understand the effects of chloride supplementation on volume-overloaded acute heart failure patients concomitantly treated with IV diuretics.
Change in Blood Volume
| Lysine Chloride | -320 ± 689 mL |
|---|---|
| Placebo | -447 ± 520 mL |
| p-value | 0.56 |
|---|
Open in BENITIONS View on ClinicalTrials.gov
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