Endovenous Corticosteroid Pulses in Moderate Ulcerative Colitis
Phase 4
Terminated
NCT02921555
| Condition | Ulcerative Colitis |
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| Phase | Phase 4 |
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| Sponsor | Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa |
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| Status | Terminated |
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| Enrollment | 75 participants |
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| Interventions | Methylprednisolone, Prednisone |
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| Start date | Oct 11, 2018 |
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| Completion date | Nov 7, 2022 |
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| Results posted | Feb 21, 2025 |
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Summary
The purpose of this study is to determine the efficacy of high-dose corticosteroid pulses added to conventional oral corticosteroid course for moderate flares of ulcerative colitis.
Percentage of Participants With Endoscopic and Clincal Remission
Change from baseline at week 8 · participants
| Methylprednisolone & Prednisone | 11 participants |
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| Prednisone | 10 participants |
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| p-value | 0.05 |
| Mean Difference (Final Values) | 16.2 |
Percentage of Participants With Endoscopic and Clinical Remission
Change from baseline at week 54 · Percentage of participants
| Methylprednisolone & Prednisone | 31 Percentage of participants |
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| Prednisone | 36 Percentage of participants |
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Open in BENITIONS
View on ClinicalTrials.gov
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