Liver Fibrosis in Zambian HIV-HBV Co-infected Patients
| Condition | Human Immunodeficiency Virus, HBV, Fibrosis, Liver, Cirrhosis, Liver |
|---|---|
| Phase | N/A |
| Sponsor | University of Alabama at Birmingham |
| Status | Completed |
| Enrollment | 349 participants |
| Interventions | Anti-HIV Agents |
| Start date | Oct, 2015 |
| Completion date | May 28, 2026 |
| Results posted | Jul 2, 2026 |
Summary
A cohort of adults with HIV-HBV co-infection will be created in Lusaka, Zambia, to describe the short and long-term (up to 10 years of follow-up) HBV and liver outcomes, including the effectiveness of current therapies, and to identify the risk factors for major endpoints of interest, including HCC and HBV functional cure. This cohort will also create a pool of potential participants for in-depth mechanistic studies and clinical trials of novel HBV cure drugs.
Reduction in Liver Fibrosis Stage
| HBV/HIV Cohort | 46 Participants |
|---|
Open in BENITIONS View on ClinicalTrials.gov
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