BENITIONSClinical Trial Intelligence

Evaluation of Advanced Imaging and Visualization for Clinical Deep Brain Stimulation

Не применимо Завершено NCT06191874

ЗаболеваниеDeep Brain Stimulation
ФазаНе применимо
СпонсорDuke University
СтатусЗавершено
Участники22 участн.
ВмешательствоStandard-of-care (SOC) surgery plan, HoloDBS hypothetical surgery plan
Дата начала1.03.2024
Дата завершения29.05.2025
Публикация результатов24.07.2026

Кратко

The objective of this project is to evaluate next generation visualization tools and surgical targeting models for clinical deep brain stimulation (DBS). This study will evaluate the performance of HoloDBS software in comparison to the current standard (SOC) clinical planning tools to prepare for DBS surgery. The investigators hypothesize that HoloDBS will provide more detailed and anatomically useful information to the neurosurgeon and neurologist than the current clinical standard. The study team reviews electronic medical records (EMR) from patients who are undergoing DBS surgery. There are no study visits involved in this study as only data from standard clinical care will be used. All study activities are executed by the study team and there are no interventions.

Distance Between the Actual Post-operative Location of the DBS Electrode and the Planned Location

1 month after surgery · mm

Surgery Planning by SOC Methods, Then by HoloDBS2.44 ± 0.90 mm
Surgery Planning by HoloDBS, Then by SOC Methods2.85 ± 1.94 mm
Surgery Planning by SOC Methods, Then by HoloDBS1.99 ± 0.86 mm
Surgery Planning by HoloDBS, Then by SOC Methods1.82 ± 0.83 mm
p-value0.1559

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