Anti-Platelets in Chronic Obstructive Pulmonary Disease

Фаза 2 Завершено NCT05567562

Заболевание	COPD, Emphysema, Emphysema or COPD
Фаза	Фаза 2
Спонсор	Brigham and Women's Hospital
Статус	Завершено
Участники	15 участн.
Вмешательство	dual anti-platelet therapy
Дата начала	27.03.2024
Дата завершения	28.02.2025
Публикация результатов	14.05.2026

Кратко

This is a 6 week crossover study in current and former smokers with and without COPD to evaluate whether 2 weeks of dual antiplatelet therapy (aspirin 81mg and clopidogrel 75mg) improves pulmonary perfusion (i.e. blood flow in the lungs measured on a contrast CT scan) compared to placebo.

Pulmonary Microvascular Blood Volume, CV

After 2 weeks of therapy · CV

On Dual Anti-platelet Therapy	0.89 ± 0.079 CV
On Placebo	0.88 ± 0.072 CV
On Dual Anti-platelet Therapy, COPD	0.92 ± 0.064 CV
On Placebo, COPD	0.91 ± 0.052 CV
On Dual Anti-platelet Therapy, Controls	0.81 ± 0.051 CV
On Placebo, Controls	0.80 ± 0.042 CV

p-value	0.84

Открыть в BENITIONS Открыть на ClinicalTrials.gov

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Все исследования

Страница обобщает открытые данные ClinicalTrials.gov. Это не медицинская и не инвестиционная рекомендация. Обратитесь к врачу.

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