BENITIONSClinical Trial Intelligence

Feasibility, Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPD

Фаза 4 Завершено NCT04655170

ЗаболеваниеCOPD Exacerbation
ФазаФаза 4
СпонсорUniversity of Tennessee Graduate School of Medicine
СтатусЗавершено
Участники60 участн.
ВмешательствоRevefenacin (YUPELRI) & Formoterol (Perforomist), Albuterol Inhalation Aerosol (short-acting beta-agonists) & Ipratropium Aerosol (short-acting anticholinergic)
Дата начала9.12.2020
Дата завершения19.01.2023
Публикация результатов3.08.2026

Кратко

The purpose of this study is to assess the feasibility, safety and efficacy of a combination of nebulized Formoterol and Revefenacin among patients hospitalized for AECOPD compared with standard-of-care therapy with nebulized Albuterol and Ipratropium.

Difference in Modified Borg Dyspnea Scale Scores Between Groups

From enrollment to the end of treatment at Day 7 · scores on a scale

Experimental: Group 1: Revefenacin (YUPELRI) & Formoterol (Perforomist)1.89 scores on a scale
Active Comparator: Group 2: Ipratropium Bromide (Atrovent) & Albuterol(Ventolin) as Standard of Care1.92 scores on a scale
p-value0.95

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