Testing Atezolizumab in People 2-17 Years Old With Clear Cell Sarcoma or Advanced Chondrosarcoma
| Заболевание | Central Chondrosarcoma, Grade 2, Central Chondrosarcoma, Grade 3, Dedifferentiated Chondrosarcoma, Metastatic Clear Cell Sarcoma of Soft Tissue |
|---|---|
| Фаза | Фаза 2 |
| Спонсор | National Cancer Institute (NCI) |
| Статус | Идёт, набор закрыт |
| Участники | 27 участн. |
| Вмешательство | Atezolizumab, Biopsy Procedure, Biospecimen Collection, Computed Tomography |
| Дата начала | 5.10.2020 |
| Дата завершения | 28.11.2022 |
| Публикация результатов | 23.10.2023 |
Кратко
This phase II trial studies how well atezolizumab works in treating patients with chondrosarcoma or clear cell sarcoma that is newly diagnosed, cannot be removed by surgery (unresectable), or has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Objective Response Rates (ORR)
| Arm 1 Atezolizumab 1200 mg Intravenous (IV) on Day 1, Subgroup 1: Clear Cell Sarcoma (CCS) | 0 percentage of participants |
|---|---|
| Arm 1 Atezolizumab 1200 mg IV on Day 1, Subgroup 2: Conventional Chondrosarcoma (CS)(Grade 2 or 3) | 0 percentage of participants |
| Arm 1 Atezolizumab 1200 mg Intravenous on Day 1, Subgroup 3: Dedifferentiated Chondrosarcoma (CS) | 0 percentage of participants |
| Arm 1 Atezolizumab 1200 mg Intravenous (IV) on Day 1, Subgroup 1: Clear Cell Sarcoma (CCS) | 0 percentage of participants |
| Arm 1 Atezolizumab 1200 mg IV on Day 1, Subgroup 2: Conventional Chondrosarcoma (CS)(Grade 2 or 3) | 0 percentage of participants |
| Arm 1 Atezolizumab 1200 mg Intravenous on Day 1, Subgroup 3: Dedifferentiated Chondrosarcoma (CS) | 0 percentage of participants |
Открыть в BENITIONS Открыть на ClinicalTrials.gov
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