Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)
| 対象疾患 | Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Refractory Lymphoma, Refractory Malignant Solid Neoplasm |
|---|---|
| 相 | 第2相 |
| スポンサー | National Cancer Institute (NCI) |
| ステータス | 実施中(募集終了) |
| 参加者数 | 19 名 |
| 介入(薬剤) | Afatinib, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test |
| 開始日 | 2018年2月28日 |
| 完了日 | 2022年12月6日 |
| 結果公開日 | 2024年12月10日 |
概要
This phase II MATCH treatment trial tests how well afatinib works in treating patients with cancer that has certain genetic changes. Afatinib is in a class of medications called kinase inhibitors. It is used in patients whose cancer has a certain mutation (change) in the EGFR gene. It works by blocking the action of mutated EGFR that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Objective Response Rate (ORR)
| Treatment (Afatinib) | 11.8 percentage of participants |
|---|
BENITIONS で見る ClinicalTrials.gov の原文を見る
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