BENITIONSClinical Trial Intelligence

Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)

第2相 実施中(募集終了) NCT06385483

対象疾患Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Refractory Lymphoma, Refractory Malignant Solid Neoplasm
第2相
スポンサーNational Cancer Institute (NCI)
ステータス実施中(募集終了)
参加者数19 名
介入(薬剤)Afatinib, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test
開始日2018年2月28日
完了日2022年12月6日
結果公開日2024年12月10日

概要

This phase II MATCH treatment trial tests how well afatinib works in treating patients with cancer that has certain genetic changes. Afatinib is in a class of medications called kinase inhibitors. It is used in patients whose cancer has a certain mutation (change) in the EGFR gene. It works by blocking the action of mutated EGFR that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Objective Response Rate (ORR)

Tumor assessments occurred at baseline, then every 2 cycles for the first 26 cycles and every 3 cycles thereafter until disease progression, up to 3 years post registration · percentage of participants

Treatment (Afatinib)11.8 percentage of participants

BENITIONS で見る ClinicalTrials.gov の原文を見る

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このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。