Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

第4相 完了 NCT05548647

概要

This study will evaluate the effect of semaglutide on eating behavior, appetite (hunger/fullness), and food liking in the long-term, as compared to placebo. All participants will receive lifestyle modification (diet and exercise) counseling, and will be prescribed the FDA-approved weight loss medication, semaglutide, or placebo (an inactive saline solution) for 72 weeks.

Study 1 Ad Libitum Energy Intake (kcal) During a Buffet Lunch Meal (4 Hrs After Standardized Breakfast)

S1: Change from baseline to weeks 20, 40, and 60 · kcal

Study 2 Ad Libitum Energy Intake (kcal) During a Buffet Lunch Meal (4 Hrs After Standardized Breakfast)

S2: Endpoint comparison at week 72 · kcal

BENITIONS で見る ClinicalTrials.gov の原文を見る

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• Diabetes Prevention Program Outcomes Study — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Effect of PDE5 Inhibition on Adipose Metabolism in Humans — Vanderbilt University Medical Center
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すべての治験