BENITIONSClinical Trial Intelligence

KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C)

第2相 完了 NCT04165096

対象疾患Carcinoma, Non-Small-Cell Lung
第2相
スポンサーMerck Sharp & Dohme LLC
ステータス完了
参加者数128 名
介入(薬剤)Pembrolizumab, Boserolimab, MK-4830, diphenhydramine, acetaminophen
開始日2020年1月21日
完了日2025年4月30日
結果公開日2026年5月13日

概要

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) in combination with boserolimab (MK-5890), MK-4830, MK-0482 in participants with advanced squamous or non-squamous NSCLC that have been previously treated with anti-PD-L1 therapy. This study is one of three pembrolizumab substudies being conducted under one pembrolizumab umbrella master protocol (MK-3475-U01/KEYMAKER-U01).

Objective Response Rate (ORR) According to Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1)

Up to approximately 53 months · Percentage of participants

Pembrolizumab + Boserolimab5.4 Percentage of participants
Pembrolizumab + MK-483011.1 Percentage of participants
Pembrolizumab + MK-04824.4 Percentage of participants

BENITIONS で見る ClinicalTrials.gov の原文を見る

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このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。