Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia
| 対象疾患 | Acute Lymphoblastic Leukemia in Remission, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
|---|---|
| 相 | 第2相 |
| スポンサー | M.D. Anderson Cancer Center |
| ステータス | 早期終了 |
| 参加者数 | 4 名 |
| 介入(薬剤) | Cyclophosphamide, Cytarabine, Dexamethasone, Doxorubicin Hydrochloride, Inotuzumab Ozogamicin |
| 開始日 | 2018年3月28日 |
| 完了日 | 2020年4月2日 |
| 結果公開日 | 2021年4月13日 |
概要
This phase II trial studies how well combination chemotherapy and inotuzumab ozogamicin work in treating patients with B acute lymphoblastic leukemia. Drugs used in chemotherapy, such as cyclophosphamide, vincristine sulfate, doxorubicin hydrochloride, dexamethasone, methotrexate and cytarabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as inotuzumab ozogamicin, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving combination chemotherapy and inotuzumab ozogamicin may work better at treating B acute lymphoblastic leukemia.
Event-Free Survival
| Treatment (Hyper-CVAD, Inotuzumab Ozogamicin) | 24 Months |
|---|
BENITIONS で見る ClinicalTrials.gov の原文を見る
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