Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial
4期
已完成
NCT05590585
| 适应症 | Moderate-to-Severe Atopic Dermatitis, Atopic Eczema |
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| 分期 | 4期 |
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| 申办方 | Regeneron Pharmaceuticals |
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| 状态 | 已完成 |
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| 受试者人数 | 124 人 |
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| 干预(药物) | dupilumab, Topical emollient (moisturizer) |
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| 开始日期 | 2023年1月11日 |
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| 完成日期 | 2024年11月14日 |
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| 结果公布日 | 2026年1月2日 |
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摘要
The study is focused on skin of color participants who have moderate-to-severe atopic dermatitis. Atopic dermatitis, also referred to as eczema, is a condition that causes the skin to become itchy, dry, and cracked. From the previous studies on the study drug, it is seen that the study drug has an acceptable safety and effectiveness in participants with atopic dermatitis. The aim of this study is to get additional information on the safety and effectiveness of the study drug, particularly the information on aspects of atopic dermatitis in skin of color participants. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in your blood at different times * How much the study drug improves quality of life and mental health
Percentage of Participants With ≥75% Reduction From Baseline in Eczema Area and Severity Index (EASI) Score (EASI-75)
Week 24 · percentage of participants
| Dupilumab | 76.0 percentage of participants |
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