BENITIONSClinical Trial Intelligence

Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment

Phase 2 Active, not recruiting NCT06502977

ConditionExtensive Stage Small Cell Lung Cancer
PhasePhase 2
SponsorAmgen
StatusActive, not recruiting
Enrollment32 participants
InterventionsTarlatamab
Start dateAug 27, 2024
Completion dateMar 28, 2025
Results postedApr 15, 2026

Summary

The primary aim of this study is to evaluate the efficacy of tarlatamab as assessed by objective response rate (ORR) based on blinded independent central review (BICR) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1).

Objective Response Rate (ORR) Based on Blinded Independent Central Review (BICR) Per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1)

From first dose of trial drug up to a minimum of last dose + 65 days or data cutoff date; median (min, max) time on trial was 3.4 (2.2, 6.5) months at data cut off · percentage of participants

Tarlatamab38.7 percentage of participants

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