BENITIONSClinical Trial Intelligence

Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Phase 2 Terminated NCT05301894

ConditionEpileptic Encephalopathy, Continuous Spike and Wave During Sleep
PhasePhase 2
SponsorNeurocrine Biosciences
StatusTerminated
Enrollment19 participants
InterventionsNBI-827104
Start dateJun 7, 2022
Completion dateJan 27, 2025
Results postedFeb 13, 2026

Summary

The primary objective for this study is to evaluate the long-term safety and tolerability of NBI-827104 in pediatric participants with epileptic encephalopathy with continuous spike-and-wave during sleep (EECSWS).

The Number of Participants With Serious Treatment-emergent Adverse Events (TEAEs)

Up to 884 days of treatment and 4-week safety follow-up (mean duration of exposure was 649.7 days) · Participants

NBI-8271042 Participants

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