BENITIONSClinical Trial Intelligence

Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer

Phase 2 Completed NCT05068752

ConditionPancreas Cancer
PhasePhase 2
SponsorHonorHealth Research Institute
StatusCompleted
Enrollment10 participants
InterventionsVemurafenib, Sorafenib
Start dateOct 28, 2021
Completion dateNov 8, 2024
Results postedMar 30, 2026

Summary

The purpose of this research is to determine the benefit of two oral chemotherapy drugs, Vemurafenib and Sorafenib, in individuals with KRAS mutated pancreatic cancer who have progressed on standard chemotherapy.

Disease Control Rate (DCR)

Initiation of study treatment until 16 weeks. · DCR, % of participants with CR/PR/SD

Vemurafenib in Combination With Sorafenib0 DCR, % of participants with CR/PR/SD

Open in BENITIONS View on ClinicalTrials.gov

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