BENITIONSClinical Trial Intelligence

Topical Ruxolitinib 1.5% for Hidradenitis Suppurativa Treatment

Phase 2 Terminated NCT04414514

ConditionHidradenitis Suppurativa
PhasePhase 2
SponsorMilton S. Hershey Medical Center
StatusTerminated
Enrollment6 participants
InterventionsRuxolitinib 1.5% Cream
Start dateOct 13, 2022
Completion dateFeb 23, 2024
Results postedApr 28, 2026

Summary

Investigators hypothesize that ruxolitinib 1.5% cream is an effective therapy for HS participants through inhibition of inflammatory activity. Investigators aim to: * Demonstrate the clinical efficacy of ruxolitinib 1.5% cream in decreasing the clinical disease activity after 16 weeks of treatment. * Investigate the impact of ruxolitinib 1.5% cream on skin inflammation through translational analyses of skin biopsy samples.

Number of Participants With Hidradenitis Suppurativa Clinical Response (HiSCR)

16 weeks after treatment. · Participants

Open-label5 Participants

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