Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma
| Condition | Gastric Adenocarcinoma, GastroEsophageal Cancer |
|---|---|
| Phase | Phase 2 |
| Sponsor | University of California, Irvine |
| Status | Completed |
| Enrollment | 34 participants |
| Interventions | Cabozantinib, Pembrolizumab |
| Start date | Feb 4, 2020 |
| Completion date | Nov 25, 2023 |
| Results posted | Aug 11, 2025 |
Summary
This is a phase 2 single-arm, open-label clinical trial determining efficacy of cabozantinib in combination with pembrolizumab in subjects with advanced gastric and gastroesophageal adenocarcinoma. These are subjects who have progressed, or not tolerated, at least one prior line of chemotherapy with a fluoropyrimidine and platinum agent.
Percentage of Participants With Progression-free Survival at 6 Months
| Cabozantinib and Pembrolizumab | 6 Participants |
|---|
Open in BENITIONS View on ClinicalTrials.gov
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