BENITIONSClinical Trial Intelligence

A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

Phase 2 Active, not recruiting NCT03069378

ConditionSarcoma, Epithelioid Sarcoma, Cutaneous Angiosarcoma
PhasePhase 2
SponsorMemorial Sloan Kettering Cancer Center
StatusActive, not recruiting
Enrollment41 participants
InterventionsTalimogene Laherparepvec (T-VEC), Pembrolizumab
Start dateMar 3, 2017
Completion dateJul 22, 2025
Results postedOct 29, 2025

Summary

The purpose of this study is to determine how well the combination of therapy of talimogene laherparepvec (T-VEC) and pembrolizumab works in the treatment of patients with sarcoma.

Best Objective Response Rate

24 weeks · Participants

Talimogene Laherparepvec (T-VEC) Administered With Pembrolizu13 Participants
Talimogene Laherparepvec (T-VEC) Administered With Pembrolizu13 Participants
Talimogene Laherparepvec (T-VEC) Administered With Pembrolizu14 Participants
Talimogene Laherparepvec (T-VEC) Administered With Pembrolizu1 Participants

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