COcoa Supplement and Multivitamin Outcomes Study
Phase 4
Completed
NCT02422745
| Condition | Cardiovascular Disease, Cancer |
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| Phase | Phase 4 |
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| Sponsor | Brigham and Women's Hospital |
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| Status | Completed |
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| Enrollment | 21,442 participants |
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| Interventions | Cocoa extract, Multivitamin, Cocoa extract placebo, Multivitamin placebo |
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| Start date | Jun, 2015 |
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| Completion date | Jul, 2022 |
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| Results posted | Sep 19, 2024 |
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Summary
The purpose of this study is to determine whether taking daily, dietary supplements of cocoa extract (containing cocoa flavanols and theobromine from the cocoa bean) and/or a standard multivitamin reduces the risk of developing cardiovascular disease (including heart attack, stroke, coronary revascularization, unstable angina or acute coronary syndrome (ACS) requiring hospitalization, carotid artery surgery, and peripheral artery surgery or angioplasty, and cardiovascular mortality) and cancer.
Number of Participants With Total Cardiovascular Disease (CVD) Events
4 years · Participants
| Active Cocoa Extract | 410 Participants |
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| Cocoa Extract Placebo | 456 Participants |
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| Active Multivitamin | 429 Participants |
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| Multivitamin Placebo | 437 Participants |
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Number of Participants With Invasive Cancer Events
4 years · Participants
| Active Cocoa Extract | 550 Participants |
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| Cocoa Extract Placebo | 503 Participants |
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| Active Multivitamin | 518 Participants |
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| Multivitamin Placebo | 535 Participants |
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Open in BENITIONS
View on ClinicalTrials.gov
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