Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss
Phase 3
Completed
NCT02008357
| Condition | Cognition Disorders |
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| Phase | Phase 3 |
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| Sponsor | Eli Lilly and Company |
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| Status | Completed |
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| Enrollment | 1,169 participants |
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| Interventions | Solanezumab |
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| Start date | Feb 28, 2014 |
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| Completion date | Dec 27, 2022 |
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| Results posted | Dec 28, 2023 |
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Summary
The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease \[AD\]).
Change From Baseline of the Preclinical Alzheimer Cognitive Composite (PACC) Score
Baseline, Week approximately 240 · score on a scale
| Solanezumab | -1.43 ± 0.21 score on a scale |
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| Placebo | -1.13 ± 0.16 score on a scale |
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| p-value | 0.260 |
| LS Mean difference (Final Values) | -0.30 (95% CI -0.816–0.220) |
Change From Baseline of the Preclinical Alzheimer Cognitive Composite (PACC) Score
Baseline, Week 336
Open in BENITIONS
View on ClinicalTrials.gov
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