BENITIONSClinical Trial Intelligence

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

Phase 3 Completed NCT02008357

ConditionCognition Disorders
PhasePhase 3
SponsorEli Lilly and Company
StatusCompleted
Enrollment1,169 participants
InterventionsSolanezumab
Start dateFeb 28, 2014
Completion dateDec 27, 2022
Results postedDec 28, 2023

Summary

The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease \[AD\]).

Change From Baseline of the Preclinical Alzheimer Cognitive Composite (PACC) Score

Baseline, Week approximately 240 · score on a scale

Solanezumab-1.43 ± 0.21 score on a scale
Placebo-1.13 ± 0.16 score on a scale
p-value0.260
LS Mean difference (Final Values)-0.30 (95% CI -0.816–0.220)

Change From Baseline of the Preclinical Alzheimer Cognitive Composite (PACC) Score

Baseline, Week 336

Open in BENITIONS View on ClinicalTrials.gov

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