Screening for Ovarian Cancer in Older Patients (PLCO Screening Trial)
N/A
Active, not recruiting
NCT01696994
| Condition | Ovarian Carcinoma, Ovarian Germ Cell Tumor |
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| Phase | N/A |
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| Sponsor | National Cancer Institute (NCI) |
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| Status | Active, not recruiting |
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| Enrollment | 78,216 participants |
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| Interventions | Laboratory Biomarker Analysis, Screening Questionnaire Administration, Ultrasound Imaging |
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| Start date | Nov 16, 1993 |
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| Completion date | May 21, 2012 |
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| Results posted | Dec 12, 2014 |
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Summary
This clinical trial studies whether screening methods used to diagnose cancer of the prostate, lung, colon, rectum, or ovaries can reduce deaths from these cancers. Screening tests may help doctors find cancer cells early and plan better treatment for ovarian cancer. The ovarian cancer screening tests are part of a trial that addresses the screening of four cancer sites, each with their own results record: prostate (NCT00002540), lung (NCT01696968), colorectal (NCT01696981), and ovarian (NCT01696994).
Ovarian Cancer Deaths (Including Primary Peritoneal and Fallopian Tube Cancers)
Events through 13 years of follow-up or through December 31, 2009; median follow-up 11.9 years. · Participants
| Control | 100 Participants |
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| Ovarian Screening | 188 Participants |
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Ovarian Cancer Death Rates (Including Primary Peritoneal and Fallopian Tube Cancers)
Events through 13 years of follow-up or through December 31, 2009; median follow-up 11.9 years. · Deaths per 10,000 PY
| Control | 2.6 Deaths per 10,000 PY |
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| Ovarian Screening | 3.1 Deaths per 10,000 PY |
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| Hazard Ratio (HR) | 1.18 (95% CI .91–1.54) |
Open in BENITIONS
View on ClinicalTrials.gov
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