BENITIONSClinical Trial Intelligence

Screening for Ovarian Cancer in Older Patients (PLCO Screening Trial)

N/A Active, not recruiting NCT01696994

ConditionOvarian Carcinoma, Ovarian Germ Cell Tumor
PhaseN/A
SponsorNational Cancer Institute (NCI)
StatusActive, not recruiting
Enrollment78,216 participants
InterventionsLaboratory Biomarker Analysis, Screening Questionnaire Administration, Ultrasound Imaging
Start dateNov 16, 1993
Completion dateMay 21, 2012
Results postedDec 12, 2014

Summary

This clinical trial studies whether screening methods used to diagnose cancer of the prostate, lung, colon, rectum, or ovaries can reduce deaths from these cancers. Screening tests may help doctors find cancer cells early and plan better treatment for ovarian cancer. The ovarian cancer screening tests are part of a trial that addresses the screening of four cancer sites, each with their own results record: prostate (NCT00002540), lung (NCT01696968), colorectal (NCT01696981), and ovarian (NCT01696994).

Ovarian Cancer Deaths (Including Primary Peritoneal and Fallopian Tube Cancers)

Events through 13 years of follow-up or through December 31, 2009; median follow-up 11.9 years. · Participants

Control100 Participants
Ovarian Screening188 Participants

Ovarian Cancer Death Rates (Including Primary Peritoneal and Fallopian Tube Cancers)

Events through 13 years of follow-up or through December 31, 2009; median follow-up 11.9 years. · Deaths per 10,000 PY

Control2.6 Deaths per 10,000 PY
Ovarian Screening3.1 Deaths per 10,000 PY
Hazard Ratio (HR)1.18 (95% CI .91–1.54)

Open in BENITIONS View on ClinicalTrials.gov

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