BENITIONSClinical Trial Intelligence

Mycophenolate Mofetil in Patients With Progressive Idiopathic Membranous Nephropathy

Phase 3 Completed NCT01282073

ConditionGlomerulonephritis, Membranous
PhasePhase 3
SponsorKyungpook National University Hospital
StatusCompleted
Enrollment43 participants
InterventionsMycophenolate mofetil, low dose steroid, Cyclosporin, low dose steroid
Start dateMar, 2011
Completion dateMay, 2016
Results postedAug 27, 2025

Summary

Cyclosporin decreases proteinuria and improve renal function in patients with idiopathic membranous nephropathy, but has a risk of side effects such as nephrotoxicity. The investigators plan to the study to evaluate whether mycophenolate mofetil (MMF) could be a reasonable alternative with fewer side effect.

Percentage of Complete Remission

at 48 week after treatment · Participants

Mycophenolate Mofetil, Low Dose Steroid4 Participants
Cyclosporin, Low Dose Steroid3 Participants

Percentage of Partial Remission

at 48 week after treatment · Participants

Mycophenolate Mofetil, Low Dose Steroid12 Participants
Cyclosporin, Low Dose Steroid9 Participants

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