BENITIONSClinical Trial Intelligence

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

Фаза 3 Прекращено NCT06635135

ЗаболеваниеDepressive Disorder, Major, Anhedonia
ФазаФаза 3
СпонсорJanssen Research & Development, LLC
СтатусПрекращено
Участники47 участн.
ВмешательствоAticaprant
Дата начала19.09.2024
Дата завершения9.04.2025
Публикация результатов8.06.2026

Кратко

The purpose of this study is to assess how well aticaprant works compared to placebo when given in addition to antidepressant therapy (selective serotonin reuptake inhibitor \[SSRI\] or serotonin-norepinephrine reuptake inhibitor \[SNRI\]) in preventing return of depression symptoms in participants with major depressive disorder who experience a loss of interest and pleasure and who achieve a stable response after treatment with adjunctive aticaprant.

Time From Randomization Into Double Blind (DB) Treatment Maintenance Phase to the First Documentation of Relapse

From date of DB randomization (Day 113) up to first documentation of relapse (up to early termination of study [Day 140]) · days

DB Treatment Maintenance Phase: Aticaprant 10 mgNA days

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