BENITIONSClinical Trial Intelligence

Study of Obeldesivir to Treat Children With Respiratory Syncytial Virus (RSV) Infection

2상 조기 종료 NCT06784973

대상 질환RSV Infection
임상 단계2상
스폰서Gilead Sciences
상태조기 종료
참여자 수4 명
중재(약물)Obeldesivir, Obeldesivir Placebo
시작일2025년 3월 5일
완료일2025년 4월 16일
결과 공개일2026년 6월 8일

요약

The goal of this clinical study is to check if obeldesivir (ODV; GS-5245) is safe and well-tolerated by children with respiratory syncytial virus (RSV) infection. It will also look at how well ODV helps reduce the time it takes for children to feel better and for their RSV symptoms to improve. The primary objectives of this study are: a) to evaluate the safety and tolerability of ODV in pediatric participants with RSV infection; b) To evaluate the efficacy of ODV on time to alleviation of targeted RSV symptoms in pediatric participants with RSV infection.

Percentage of Participants Who Experienced Treatment-Emergent Adverse Events (TEAEs) by Day 28

Up to Day 28 · percentage of participants

Cohort 1: Part A (Group 2) - Obeldesivir (ODV)0 percentage of participants
Cohort 1: Part A (Group 3) - ODV100.0 percentage of participants
Cohort 1: Part A (Group 3) - Placebo100.0 percentage of participants

Percentage of Participants Who Experienced Grade 3 or 4 Treatment-Emergent Laboratory Abnormalities by Day 28

Up to Day 28 · percentage of participants

Cohort 1: Part A (Group 2) - Obeldesivir (ODV)0 percentage of participants
Cohort 1: Part A (Group 3) - ODV0 percentage of participants
Cohort 1: Part A (Group 3) - Placebo100.0 percentage of participants

Time to Alleviation of Targeted Respiratory Syncytial Virus (RSV) Symptoms by Day 28

Up to Day 28 · days

Cohort 1: Part A (Group 2) - Obeldesivir (ODV)5.4 days
Cohort 1: Part A (Group 3) - ODVNA days

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