BENITIONSClinical Trial Intelligence

A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants

2상 완료 NCT06454630

대상 질환Venous Thromboembolism
임상 단계2상
스폰서Regeneron Pharmaceuticals
상태완료
참여자 수179 명
중재(약물)REGN7508, Enoxaparin
시작일2024년 6월 27일
완료일2024년 11월 19일
결과 공개일2026년 3월 2일

요약

This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on adults undergoing elective, unilateral (one side) total knee replacement (TKR) surgery. The aim of the study is to see how effective the study drug is at preventing venous thromboembolism (VTE) and other related diseases after unilateral total knee replacement surgery. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)

Percentage of Participants With Confirmed, Adjudicated Venous Thromboembolism (VTE)

Through day 12 · percentage of participants

REGN75087.1 percentage of participants
Enoxaparin17.2 percentage of participants
Posterior Odds Ratio0.37

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